Protein concentration and filtration

Protein production require adequate monitoring and control for maximizing yield and to obtain the desired level of purity. Downstream operations such as diafiltration, desalting and buffer exchange e.g. by ultrafiltration are common steps used for concentration and purification that require efficient concentration control as they are critical for final yield and quality.

Download our application note and learn how, by utilizing real-time concentration measurements by Vaisala Polaris™ Refractometer, pharmaceutical manufacturers can:

Monitor in real-time protein and buffer concentration during concentration, desalting or buffer exchange
Ensure correct protein buffer concentrations
Maximize product yield in each step and guarantee purity of proteins
Adjust concentration levels after ultrafiltration

The application note explains in more detail the benefits of using refractive index in biopharmaceuticals manufacturing and why refractometer is ideal for protein concentration and filtration. The note also includes recommended installation points for best performance.

Download the application note (PDF) by filling the form.

Discover all applications in Pharmaceutical drug manufacturing and biotechnology processes.

Email Address*

First Name*

Last Name*

Country*

State or Province*

Company*

Choose your industry*

Title

Business Phone*

I authorize Vaisala to send me information about relevant products and services.

See our Privacy Policy for more details.
You can modify your preference settings or unsubscribe at any time here