vH2O2 Bio-decontamination: Optimizing Cycle Development in Aseptic Isolators

Vaporized hydrogen peroxide is an effective antimicrobial that also destroys fungal spores, bacterial endospores, and viruses. While isolators prevent contamination, to maintain aseptic conditions, vH₂O₂ bio-decontamination is performed on the internal surfaces of the isolator and the exposed, external surfaces of the materials and equipment placed within. Understanding and controlling process conditions throughout all phases of vH₂O₂ bio-decontamination is crucial to effective log kills.

To develop an effective bio-decontamination cycle, measurements of process conditions like temperature, humidity, vH₂O₂ concentration (ppm), and condensation point are necessary.  In addition to measuring and monitoring parameters, an understanding of aseptic techniques, glove management, isolator preparation, process indicators, and validation are all important to successful vH₂O₂ bio-decontamination processes. 

In this webinar, Vaisala Product Manager Joni Partanen is joined by Rick Nieskes of Ardien Consulting. Rick brings over thirty years of industry experience to show how to optimize cycle development for vH₂O₂ bio-decontamination in pharmaceutical isolators. Joni will describe the unique technology of Vaisala's vH₂O₂ sensor and the importance of calibration and maintenance of these sensors, exposed to the demanding conditions of vH₂O₂ bio-decontamination.

After the webinar, our presenters shared their Q&A in these two blogs:

Part 1 – Questions & answers on vH2O2 bio-decontamination in aseptic isolators
Part 2 – Questions & answers on vH2O2 bio-decontamination in aseptic isolators